Faculty of Bioscience and Applied Chemistry

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BLS300YB(生物科学 / Biological science 300)


Class code etc
Faculty/Graduate school Faculty of Bioscience and Applied Chemistry
Attached documents
Year 2022
Class code H7571
Previous Class code
Previous Class title
Term 春学期授業/Spring
Day/Period 木4/Thu.4
Class Type
Campus 小金井
Classroom name 各学部・研究科等の時間割等で確認
Notes 成績優秀者の他学部科目履修制度で履修する学
Open Program
Open Program (Notes)
Global Open Program
Interdepartmental class taking system for Academic Achievers
Interdepartmental class taking system for Academic Achievers (Notes)
Class taught by instructors with practical experience
Urban Design CP
Diversity CP
Learning for the Future CP
Carbon Neutral CP
Chiyoda Campus Consortium
Category 生命機能学科

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Outline and objectives

In concrete terms, what is "energy" within a living organism? How is energy conveyed, stored, and transformed within our bodies? Is it all about ATP? These interesting questions and many more will be addressed throughout this course. At the end, the student is expected to master the basic elements of biothermodynamics, and have a clear idea about the process of life.


The enrolled student should be able to understand how the process of energy capture, and its storage and conversion into active processes is carried out within living organisms. Basic concepts of thermodynamics will be explained.

Which item of the diploma policy will be obtained by taking this class?


Default language used in class

英語 / English

Method(s)(学期の途中で変更になる場合には、別途提示します。 /If the Method(s) is changed, we will announce the details of any changes. )

This course is delivered in the form of sequential lectures. Students are encouraged to participate actively in discussions, and inquiries are welcomed at any time when concepts are not clear. Most part of the didactic materials will be made available through the support system Hoppii.
To assess the adequate understanding of classes, reports and responses to quizzes will be requested periodically, and scored appropriately, and their solutions will be discussed in following classes. Should any topic still remain unclear, appropriate discussions can be scheduled using office hours.
As COVID-19 pandemic situation persists, classes can also be delivered in online format.

Active learning in class (Group discussion, Debate.etc.)

あり / Yes

Fieldwork in class

なし / No


授業形態/methods of teaching:対面/face to face


1[対面/face to face]:Introduction

What is bioenergetics about?

2[対面/face to face]:Basic Thermodynamics.

Concept of "free energy", enthalpy, and entropy. Systems in equilibrium.

3[対面/face to face]:Redox reactions (1)

The simplest case: carbon in all oxidation states. Reduction-oxidation (redox) potential.

4[対面/face to face]:Redox reactions (2)

Chemical reactions involving reduction and oxidation in biological systems.

5[対面/face to face]:Redox reactions (3)

Spontaneity of chemical reactions. Enzyme reactions.

6[対面/face to face]:Mid-term recap

Consolidation of concepts expressed in previous classes.

7[対面/face to face]:The "mysterious" ATP.

The pending question: Where in ATP is the energy "stored"? And how it is released. Other compounds.

8[対面/face to face]:Bioenergetics (1)

Glycolysis. Why glucose?

9[対面/face to face]:Bioenergetics (2)

Krebs (TCA) cycle. Electron and proton transporters. This is the core of life sustenance at molecular level.

10[対面/face to face]:Bioenergetics (3)

Inside the mitochondrion. Electron transport chain. ATP production. Chemiosmotic theory.

11[対面/face to face]:Bioenergetics (4)

Photosynthesis. Similarities and differences with animal metabolism.

12[対面/face to face]:Bioenergetics (5)

Use of inhibitors of the electron transport chain. P/O ratio.

13[対面/face to face]:Role of ATP.

Endergonic and exergonic reactions. Coupled reactions. Typical misconceptions.

14[対面/face to face]:Recapitulation of previous lectures.

Bioenergetics and the sustenance of life. Closing remarks.

Work to be done outside of class (preparation, etc.)

【本授業の準備・復習等の授業時間外学習は、4時間を標準とする】Periodically, quizzes and homework will be assigned to students, and these will be presented as reports. All will be solved and explained in following classes to consolidate learned concepts.


The textbooks mentioned below can be used partially, although its purchase is not necessary.
"Biological Thermodynamics", Donald T. Haynie, Cambridge, 2001.
「生体とエネルギーの物理-生命力のみなもと」,日本物理学会 集(2000)の一部を利用する。


Prior to classes, appropriate handouts or other materials will be made available through the support system Hoppii.

Grading criteria

In principle, assistance to classes is required. Active participation will be graded accordingly (20%). Grading will be also based on periodic short tests, some of which will take the form of homework (30%). Final test or its equivalent (50%).

Changes following student comments

Should the COVID-19 pandemic situation persist, the online course has been also implemented for the present academic year.
Quizzes and short test will be discussed in class to consolidate learned concepts.

Equipment student needs to prepare

In case of online classes, laptops or personal computers with audiovisual capabilities and reliable internet connection will be required. Also this equipment will be necessary for the submission of electronic reports.