生命科学部Faculty of Bioscience and Applied Chemistry
BLS300YB（生物科学 / Biological science 300）バイオエナジェティクスBioenergetics
常重 アントニオAntonio TSUNESHIGE
授業コードなどClass code etc
| 学部・研究科Faculty/Graduate school | 生命科学部Faculty of Bioscience and Applied Chemistry |
| 添付ファイル名Attached documents | |
| 年度Year | 2022 |
| 授業コードClass code | H7571 |
| 旧授業コードPrevious Class code | |
| 旧科目名Previous Class title | |
| 開講時期Term | 春学期授業/Spring |
| 曜日・時限Day/Period | 木4/Thu.4 |
| 科目種別Class Type | |
| キャンパスCampus | 小金井 |
| 教室名称Classroom name | 各学部・研究科等の時間割等で確認 |
| 配当年次Grade | |
| 単位数Credit(s) | |
| 備考（履修条件等）Notes |
成績優秀者の他学部科目履修制度で履修する学 生：教員の受講許可が必要(オンライン授業の場合は、学習支援システムで許可を得るようにする) |
| 他学部公開科目Open Program | |
| 他学部公開（履修条件等）Open Program (Notes) | |
| グローバル・オープン科目Global Open Program | |
| 成績優秀者の他学部科目履修制度対象Interdepartmental class taking system for Academic Achievers | ○ |
| 成績優秀者の他学部科目履修（履修条件等）Interdepartmental class taking system for Academic Achievers (Notes) | |
| 実務経験のある教員による授業科目Class taught by instructors with practical experience | ○ |
| SDGsCPSDGs CP | |
| アーバンデザインCPUrban Design CP | |
| ダイバーシティCPDiversity CP | |
| 未来教室CPLearning for the Future CP | |
| カーボンニュートラルCPCarbon Neutral CP | |
| 千代田コンソ単位互換提供（他大学向け）Chiyoda Campus Consortium | |
| カテゴリー＜生命科学部＞Category |
生命機能学科 学科専門科目 |
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授業の概要と目的（何を学ぶか）Outline and objectives
In concrete terms, what is "energy" within a living organism? How is energy conveyed, stored, and transformed within our bodies? Is it all about ATP? These interesting questions and many more will be addressed throughout this course. At the end, the student is expected to master the basic elements of biothermodynamics, and have a clear idea about the process of life.
（本科目は，グローバル対応科目である）。
到達目標Goal
The enrolled student should be able to understand how the process of energy capture, and its storage and conversion into active processes is carried out within living organisms. Basic concepts of thermodynamics will be explained.
この授業を履修することで学部等のディプロマポリシーに示されたどの能力を習得することができるか（該当授業科目と学位授与方針に明示された学習成果との関連）Which item of the diploma policy will be obtained by taking this class?
DP2
授業で使用する言語Default language used in class
英語 / English
授業の進め方と方法Method(s)（学期の途中で変更になる場合には、別途提示します。 /If the Method(s) is changed, we will announce the details of any changes. ）
This course is delivered in the form of sequential lectures. Students are encouraged to participate actively in discussions, and inquiries are welcomed at any time when concepts are not clear. Most part of the didactic materials will be made available through the support system Hoppii.
To assess the adequate understanding of classes, reports and responses to quizzes will be requested periodically, and scored appropriately, and their solutions will be discussed in following classes. Should any topic still remain unclear, appropriate discussions can be scheduled using office hours.
As COVID-19 pandemic situation persists, classes can also be delivered in online format.
アクティブラーニング（グループディスカッション、ディベート等）の実施Active learning in class (Group discussion, Debate.etc.)
あり / Yes
フィールドワーク（学外での実習等）の実施Fieldwork in class
なし / No
授業計画Schedule
授業形態/methods of teaching：対面/face to face
※各回の授業形態は予定です。教員の指示に従ってください。
1[対面/face to face]：Introduction
What is bioenergetics about?
2[対面/face to face]：Basic Thermodynamics.
Concept of "free energy", enthalpy, and entropy. Systems in equilibrium.
3[対面/face to face]：Redox reactions (1)
The simplest case: carbon in all oxidation states. Reduction-oxidation (redox) potential.
4[対面/face to face]：Redox reactions (2)
Chemical reactions involving reduction and oxidation in biological systems.
5[対面/face to face]：Redox reactions (3)
Spontaneity of chemical reactions. Enzyme reactions.
6[対面/face to face]：Mid-term recap
Consolidation of concepts expressed in previous classes.
7[対面/face to face]：The "mysterious" ATP.
The pending question: Where in ATP is the energy "stored"? And how it is released. Other compounds.
8[対面/face to face]：Bioenergetics (1)
Glycolysis. Why glucose?
9[対面/face to face]：Bioenergetics (2)
Krebs (TCA) cycle. Electron and proton transporters. This is the core of life sustenance at molecular level.
10[対面/face to face]：Bioenergetics (3)
Inside the mitochondrion. Electron transport chain. ATP production. Chemiosmotic theory.
11[対面/face to face]：Bioenergetics (4)
Photosynthesis. Similarities and differences with animal metabolism.
12[対面/face to face]：Bioenergetics (5)
Use of inhibitors of the electron transport chain. P/O ratio.
13[対面/face to face]：Role of ATP.
Endergonic and exergonic reactions. Coupled reactions. Typical misconceptions.
14[対面/face to face]：Recapitulation of previous lectures.
Bioenergetics and the sustenance of life. Closing remarks.
授業時間外の学習（準備学習・復習・宿題等）Work to be done outside of class (preparation, etc.)
【本授業の準備・復習等の授業時間外学習は、4時間を標準とする】Periodically, quizzes and homework will be assigned to students, and these will be presented as reports. All will be solved and explained in following classes to consolidate learned concepts.
テキスト（教科書）Textbooks
The textbooks mentioned below can be used partially, although its purchase is not necessary.
"Biological Thermodynamics", Donald T. Haynie, Cambridge, 2001.
「生体とエネルギーの物理－生命力のみなもと」，日本物理学会 集（2000）の一部を利用する。
参考書References
Prior to classes, appropriate handouts or other materials will be made available through the support system Hoppii.
成績評価の方法と基準Grading criteria
In principle, assistance to classes is required. Active participation will be graded accordingly (20%). Grading will be also based on periodic short tests, some of which will take the form of homework (30%). Final test or its equivalent (50%).
学生の意見等からの気づきChanges following student comments
Should the COVID-19 pandemic situation persist, the online course has been also implemented for the present academic year.
Quizzes and short test will be discussed in class to consolidate learned concepts.
学生が準備すべき機器他Equipment student needs to prepare
In case of online classes, laptops or personal computers with audiovisual capabilities and reliable internet connection will be required. Also this equipment will be necessary for the submission of electronic reports.