生命科学部Faculty of Bioscience and Applied Chemistry
BLS300YB（生物科学 / Biological science 300）バイオエナジェティクスBioenergetics
常重 アントニオAntonio TSUNESHIGE
授業コードなどClass code etc
| 学部・研究科Faculty/Graduate school | 生命科学部Faculty of Bioscience and Applied Chemistry |
| 添付ファイル名Attached documents | |
| 年度Year | 2021 |
| 授業コードClass code | H7571 |
| 旧授業コードPrevious Class code | |
| 旧科目名Previous Class title | |
| 開講時期Term | 春学期授業/Spring |
| 曜日・時限Day/Period | 木4/Thu.4 |
| 科目種別Class Type | |
| キャンパスCampus | 小金井 |
| 教室名称Classroom name | |
| 配当年次Grade | |
| 単位数Credit(s) | |
| 備考（履修条件等）Notes |
成績優秀者の他学部科目履修制度で履修する学 生：教員の受講許可が必要(オンライン授業の場合は、学習支援システムで許可を得るようにする) |
| 他学部公開科目Open Program | |
| 他学部公開（履修条件等）Open Program (Notes) | |
| グローバル・オープン科目Global Open Program | |
| 成績優秀者の他学部科目履修制度対象Interdepartmental class taking system for Academic Achievers | ○ |
| 成績優秀者の他学部科目履修（履修条件等）Interdepartmental class taking system for Academic Achievers (Notes) | |
| 実務経験のある教員による授業科目Class taught by instructors with practical experience | ○ |
| SDGsCPSDGs CP | |
| アーバンデザインCPUrban Design CP | |
| ダイバーシティCPDiversity CP | |
| 未来教室CPLearning for the Future CP | |
| カーボンニュートラルCPCarbon Neutral CP | |
| 千代田コンソ単位互換提供（他大学向け）Chiyoda Campus Consortium | |
| カテゴリー＜生命科学部＞Category |
生命機能学科 学科専門科目 |
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授業の概要と目的（何を学ぶか）Outline and objectives
In concrete terms, what is "energy" within a living organism? How is energy conveyed, stored, and transformed within our bodies? Is it all about ATP? These interesting questions and many more will be addressed throughout this course. At the end, the student is expected to master the basic elements of biothermodynamics, and have a clear idea about the process of life.
（本科目は，グローバル対応科目である）。
到達目標Goal
The enrolled student should be able to understand how the process of energy capture, and its storage and conversion into active processes is carried out within living organisms. Basic concepts of thermodynamics will be provided.
この授業を履修することで学部等のディプロマポリシーに示されたどの能力を習得することができるか（該当授業科目と学位授与方針に明示された学習成果との関連）Which item of the diploma policy will be obtained by taking this class?
DP2
授業で使用する言語Default language used in class
英語 / English
授業の進め方と方法Method(s)（学期の途中で変更になる場合には、別途提示します。 /If the Method(s) is changed, we will announce the details of any changes. ）
This course is delivered in the form of sequential lectures. Students are encouraged to participate actively in discussions, and inquiries are welcomed at any time when concepts are not clear. Most part of the didactic materials will be made available through the support system Hoppii.
To assess the adequate understanding of classes, reports will be requested periodically to enrolled students, and will be submitted electronically. Solution to quizzes and problems will be discussed at the beginning of the following class. Should any topic still remain unclear, appropriate discussions can be scheduled using office hours.
アクティブラーニング（グループディスカッション、ディベート等）の実施Active learning in class (Group discussion, Debate.etc.)
あり / Yes
フィールドワーク（学外での実習等）の実施Fieldwork in class
なし / No
授業計画Schedule
※各回の授業形態は予定です。教員の指示に従ってください。
1：Introduction
What is bioenergetics about?
2：Basic Thermodynamics.
Concept of "free energy", enthalpy, and entropy. Systems in equilibrium.
3：Redox reactions 1)
The simplest case: carbon in all oxidation states. Reduction-oxidation (redox) potential.
4：Redox reactions (2)
Chemical reactions involving reduction and oxidation in biological systems.
5：Redox reactions (3)
Spontaneity of chemical reactions. Enzyme reactions.
6：Mid-term recap
Consolidation of concepts expressed in previous classes.
7：The "mysterious" ATP.
The pending question: Where in ATP is the energy "stored"? And how it is released. Other compounds.
8：Bioenergetics (1)
Glycolysis. Why glucose?
9：Bioenergetics (2)
Krebs (TCA) cycle. Electron and proton transporters. This is the core of life sustenance at molecular level.
10：Bioenergetics (3)
Inside the mitochondrion. Electron transport chain. ATP production. Chemiosmotic theory.
11：Bioenergetics (4)
Photosynthesis. Similarities and differences with animal metabolism.
12：Bioenergetics (5)
Use of inhibitors of the electron transport chain. P/O ratio.
13：Role of ATP.
Endergonic and exergonic reactions. Coupled reactions. Typical misconceptions.
14：Recapitulation of previous lectures.
Bioenergetics and the sustenance of life. Closing remarks.
授業時間外の学習（準備学習・復習・宿題等）Work to be done outside of class (preparation, etc.)
【本授業の準備・復習等の授業時間外学習は、4時間を標準とする】Periodically, homework will be assigned to students to consolidate learned concepts. These will be presented as reports.
テキスト（教科書）Textbooks
The textbooks mentioned below can be used partially, although its purchase is not necessary.
"Biological Thermodynamics", Donald T. Haynie, Cambridge, 2001.
「生体とエネルギーの物理－生命力のみなもと」，日本物理学会 集（2000）の一部を利用する。
参考書References
Appropriate handouts will be made available through the support system Hoppii, prior classes.
成績評価の方法と基準Grading criteria
In principle, assistance to classes is required. Active participation will be graded accordingly (20%). Grading will be also based on periodic short tests, some of which will take the form of homework (30%). Final test or its equivalent (50%).
学生の意見等からの気づきChanges following student comments
Due to the current COVID-19 pandemic, this course has been implemented since the year 2020 for real-time online delivery, that allows attendance of overseas students. The same conditions apply for the academic year 2021. Should conditions permit, in addition to the online format, in-person classes will be implemented.
Quizzes and short test will be discussed in class.
学生が準備すべき機器他Equipment student needs to prepare
Except bringing personal computers to class, nothing special.